Efficacy of Live Attenuated Dengue Vaccines: CYD-TDV; TDV (TAK-003) and TV003/TV005

Highlight:Differences in the efficacy of CYD-TDV versus other TAK-003 and TV003/TV005 were discussed.One licensed dengue vaccine is (Dengvaxia). Abstract:Dengue fever most common tropical disease, but there still remains no specific therapy that can overcome it. Special attention needs to be paid this because large increases incidence last decade. As an effective preventive strategy, finding a new for with higher potentiation highly necessary stop transmission especially endemic area. Vaccine triggers immune response, so it create robust response when infected. Nowadays, only one However, has many weaknesses, namely its dependency on serostatus recipient. There are also vaccines ongoing clinical testing have promising results, TDV (TAK-003) TV003/TV005. These three live attenuated various results. This review discussed differences against TV003/TV005; considering known unknown factors.